ISPINE- IV Therapy

The Ketamine begins to take effect about 5 minutes after the start of the IV infusion. Patients often report feeling calm, relaxed, euphoric and sometimes that their mind is fully engaged but appear to be sleeping.

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ISPINE Sports Medicine and Pain Management, PA
Houston, TX and Keller/Southlake, TX

ISPINE strives to provide the top IV pain therapy in Texas available to patients who suffer from chronic pain. With board certified physicians and pain management specialists led by Dr. Reginald Newsome, we are happy to introduce you to Ketamine Infusions – a safe and effective new treatment that is ideal for decreasing nerve pain levels in patients with chronic pain.


Ketamine has been used for many years is a and was first approved by the FDA for use in humans in 1970. Used as a surgical anesthetic during the Vietnam War, Ketamine grew in popularity due to its safety, tolerability, and ability to effectively treat pain. Ketamine has “dissociative” properties whereby the patient’s consciousness is detached from their nervous system and therefore blocking the pain the patient feels. By shutting off the communication pathways between the brain and body, Ketamine is ideal for the treatment of painful conditions such as complex regional pain syndrome (CRPS), migraine headaches, spinal cord injuries, fibromyalgia, and other nerve pain conditions. Together with the nerve pain management experts at ISPINE, you’ll receive a series of treatments by certified top IV therapy for pain management in Texas that are designed to help reduce pain over a longer period of time. If you’re seeking help for pain management, please contact one of ISPINE’s two offices to schedule a detailed evaluation – (346) 330-9966 or book your appointment online today.

Ketamine Infusion Treatment Information


The Ketamine Infusion takes about 4 hours, although the actual IV infusion is about 3 hours. You’ll be with your team for 10-20 minutes before the appointment as they explain the treatment and address questions. The Ketamine begins to take effect about 5 minutes after the start of the IV infusion. Patients often report feeling calm, relaxed, euphoric and sometimes that their mind is fully engaged but appear to be sleeping. The dissociation is described as the separation of the brain and body. The effects of Ketamine wear off within 15-30 minutes after the infusion. Overall, the experience should be very pleasant. Sedation is optional, and a CRNA will supervise you during your appointment.


ISPINE delivers Ketamine Infusions to patients over a period of time. The first phase is the “Stabilization” phase which consists of three total IV treatments. It is recommended that there is at least one day between treatments, with a maximal of five days. The stabilization period is designed to build on the previous treatment to reach higher Ketamine doses and is timed so that patients overcome any slight tolerance to medication and increase pain relieving properties. Clinical evidence shows a higher level of Ketamine translates to a reduction in pain experienced. The “Maintenance” phase follows the initial stabilization phase and begins anywhere from six days, and up to thirty days after the stabilization cycle ends. How the patient responds to the initial treatment will determine how often they receive maintenance treatment.


  • Complex regional pain syndrome (CRPS)
  • Fibromyalgia
  • Migraines
  • Spinal cord injuries
  • Phantom limb after amputation
  • Poststroke pain
  • TMJ pain
  • Facial pain
  • Small fiber neuropathy
  • Reflex sympathetic dystrophy (RSD)


There is virtually no chance for addiction with Ketamine under the supervision of ISPINE personnel as the patient receives relatively small doses during an infusion. While the patient will build a tolerance, that tolerance will diminish quickly over time. Additionally, Ketamine does not act on addiction centers in the brain as do typical “addictive medications” such as opioids. Moreover, one of the most significant benefits of Ketamine is that the effects only last for a short period of time whereby making addiction and abuse very unlikely if used correctly with a physician.


If you are suffering from chronic or acute pain and need relief, please contact ISPINE and let’s talk about a pain management treatment plan that is right for you. You just might be a good candidate for Ketamine Infusions. With offices located in both Houston and Dallas, please schedule your appointment by calling (346) 330-9966 or book your appointment online today.

IV Therapy Add-ONs:

Active Ingredients

Vitamin B1

Thiamine is an essential nutrient and must be obtained from the diet. B1 helps the body make new cells and has immune protective properties. Studies show that this vitamin is necessary to help break down simple carbohydrates and covert them to usable energy.

Vitamin B2

Riboflavin, like other B vitamins assists in the metabolism of fats, carbohydrates and proteins lending to energy production. Riboflavin is also important for red blood cell production, which is necessary for transporting oxygenated blood throughout the body. It is essential for healthy skin, hair growth, and thyroid regulation and has been known to prevent and treat migraine headaches, cataracts, rheumatoid arthritis, and some skin disorders.

Vitamin B3

Niacin works closely with other B vitamins to convert food into energy. It aids in the production of hydrochloric acid which is needed for proper digestion. Niacin plays a role in detoxification and helps support the adrenal glands. One of the primary uses for niacin is to boost HDL cholesterol (i.e. the good cholesterol).

Vitamin B5

Like other B vitamins, Vitamin B5 helps the body convert carbohydrates, fats, and proteins into energy. It is the most important component of coenzyme A, which assists in several metabolic pathways and is necessary for the transfer of fats to and from cells. Without it, fats could not be metabolized to energy. B5 produces numerous enzymes and helps maintain communication between the central nervous system and the brain. It contributes to the production of sex and stress-related hormones in the adrenal glands, which is why it can help handle stressors, both emotional and physical. Vitamin B5 is also important in maintaining a healthy digestive tract and maintaining good health.

Vitamin B6

Vitamin B6 helps the body extract energy from carbohydrates, fats, and proteins. Vitamin B6 is also a major player in mood and sleep patterns because it helps the body produce neurotransmitters such as serotonin for maintaining mood balance and melatonin to help the body regulate the sleep cycle.

Vitamins B6, along with vitamins B12 and B9 (folic acid) helps control blood levels of homocysteine – an amino acid that may be associated with heart disease. Your body needs B6 in order to absorb vitamin B12 and to make red blood cells.

Vitamin B12

Majority of people are not getting enough Vit B12! Vitamin B-12, or Cobalamin, is the largest and most complex vitamin and cannot be made by the body so it must be obtained from food or supplementation. Some people do not consume enough vitamin B-12 to meet their needs, while others cannot absorb enough.

Vitamin B12 helps maintain healthy nerve cells, aids in the production of DNA and RNA which is the genetic material important for growth and development. It is essential for the proper production of blood platelets and red and white blood cells and even a slight deficiency of this vitamin will cause anemia, fatigue and/or depression.

Vitamin B-Complex

Vitamin B-Complex is a water soluble group of vitamins that include B1, B2, B3, B5, B6, B9, B12 and plays many important roles in the body. Vitamin B complex improves the body’s resistance to stress, aids in digestion, promotes healthy skin, reduces muscle spasms, leg cramps, and helps regulate blood pressure. Vitamin B complex is involved in energy production, detoxification, nerve transmission, blood formation, synthesis of proteins and fats, the production of steroid hormones and the maintenance of blood sugar levels.

Vitamin C
Ascorbic Acid

Vitamin C, also known as ascorbic acid in its metabolically active form, is necessary for the growth, development and repair of all body tissues and it is involved in many body functions, including supporting cartilage, bones, teeth, immune system, wound healing and collagen formation.

Vitamin C is known as a super-antioxidant. Antioxidants are molecules that allow checks and balances of chemical reactions in our body. Free radical molecules can damage our cells and tissues leading to health issues such as cancer, heart disease and arthritis. Antioxidants help prevent the formation, activity and buildup of free radical molecules. The aging process is largely responsible for the build up of free radicals.

Calcium Gluconate

Calcium is an essential dietary element, and is important for the maintenance of a normal heartbeat, for the normal functioning of nerves and muscle contraction, the release of neurotransmitters and hormones, proper enzyme function and blood coagulation. Calcium in used by the body as a building block for healthy bones and teeth.


Carnitine is a naturally occurring nutrient produced by the liver, brain and kidneys. It allows the transport of fatty acids into the cells to produce energy which makes it a well known “fat burner”. Carnitine supplementation has been shown to aid in muscle recovery after exercise, decrease soreness, improve vascular function and improved antioxidant effects.


Glutathione is the most important molecule you need to stay healthy and prevent aging – it is the mother of all antioxidants! Your body produces its own glutathione however that production wanes as we age due to poor diet, pollution, toxins, medications, stress, aging, and radiation.

Some of the many benefits of Glutathione are:

  • increased energy
  • improved recovery from physical activity
  • improved skin conditioning
  • immune system support
  • detoxification
  • disease prevention
  • slows aging process
  • liver, digestive, circulatory, brain support

Glutathione removes toxins in the body and when there is an overload of toxins along with decreased production of Glutathione this leaves you susceptible to unrestrained cell disintegration from oxidative stress, free radicals, infections and cancer. The liver gets overloaded and damaged, making it unable to do its job of detoxification.


Magnesium is the fourth most abundant mineral in our bodies and is needed for hundreds of biochemical reactions mostly in your bones, muscles, nerves and brain. It helps support a healthy heartbeat and immune system. It contributes to blood glucose regulation and the production of energy and protein. Magnesium is known as a relaxation mineral and is good for muscle cramps, mood swings, insomnia and blood pressure regulation.


Zinc is an essential trace mineral. Every cell in the body needs this nutrient to properly function. Many metabolic cascades rely on it, from the immune system to the regulation of blood sugar.

The body does not produce zinc on its own, so its crucial that it is obtained through your diet and supplementation. Evidence exists that zinc supplements may also be useful for fighting cold and flu symptoms and has shown benefits for promoting recovery from skin injuries, and controlling acne and eye problems.

If you desire pain relief and your life restored...